Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.50 |
| ▸ | ITGAL | P20701 | 2/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGFR | P43088 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925948 | 1.00 | MIF (0.54) | MIFITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL1233597 | 0.87 | MIF (0.67) | MIFITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL30278657 | 0.87 | MIF (0.67) | MIFITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL29414316 | 0.87 | MIF (0.67) | MIFITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL1233600 | 0.87 | MIF (0.67) | MIFITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL27559497 | 0.85 | MAPT (0.42) | MIFMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL65191 | 0.85 | TDO2 (0.58) | MIFLMNATDO2CA1CA2 | |
| SCHEMBL65190 | 0.85 | TDO2 (0.58) | MIFLMNATDO2CA1CA2 | |
| SCHEMBL14086377 | 0.85 | TDO2 (0.58) | MIFLMNATDO2CA1CA2 | |
| SCHEMBL29535211 | 0.85 | TDO2 (0.58) | MIFLMNATDO2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042378-A1 | SUBSTITUTED CYANOBUTYRATES HAVING HERBICIDAL EFFECT | BASF SE (DE) | 2011-04-14 | — | — | WO | disclosed |
| US-20080200731-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-7381832-B2 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-03 | — | — | US | disclosed |
| US-20050234264-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6956129-B2 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-10-18 | — | — | US | disclosed |
| US-20020115885-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234264-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | MIF 878/4885ITGB2 3345/4885ICAM1 1324/4885 |
| US-20080200731-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | MIF 878/4885ITGB2 3345/4885ICAM1 1324/4885 |
| US-20020115885-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | MIF 734/4885ITGB2 3628/4885ICAM1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.