Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828225 | 1.00 | MIF (0.51) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29414316 | 0.86 | MIF (0.67) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1233597 | 0.86 | MIF (0.67) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30278657 | 0.86 | MIF (0.67) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1233600 | 0.86 | MIF (0.67) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30310600 | 0.77 | HDAC3 (0.50) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22046677 | 0.77 | HDAC3 (0.50) | MIFHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1674366 | 0.75 | MIF (0.54) | MIFGPR183TBXA2RPTGFRPTGER3 | |
| SCHEMBL4925948 | 0.75 | MIF (0.54) | MIFGPR183TBXA2RPTGFRPTGER3 | |
| SCHEMBL4716770 | 0.73 | ERCC5 (0.70) | ERCC5FEN1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |