Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952085 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL24209689 | 0.89 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL21952039 | 0.84 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL30278757 | 0.84 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL21952006 | 0.83 | HPGD (0.47) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL30278755 | 0.83 | HPGD (0.47) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL28929896 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL22010404 | 0.74 | KMO (0.41) | ALDH1A1MEN1KMT2AKMOKDM1A | |
| SCHEMBL29798314 | 0.71 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL21952043 | 0.71 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-B | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2025-03-04 | — | — | CN | disclosed |
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |