Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | SLCO1B3 | Q9NPD5 | 6/20 | 0.62 |
| ▸ | SLCO1B1 | Q9Y6L6 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azadiradione SCHEMBL19588462 | 0.90 | CYP3A4 (0.77) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| Azadiradione SCHEMBL29398035 | 0.90 | CYP3A4 (0.77) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL17368654 | 0.82 | CYP3A4 (0.74) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL10019478 | 0.77 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL598727 | 0.77 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL9973669 | 0.77 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL17616912 | 0.77 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL14197006 | 0.77 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL20639350 | 0.77 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 | |
| SCHEMBL9973671 | 0.76 | CYP3A4 (0.85) | CYP3A4SMN1; SMN2SLCO1B3SLCO1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142498-A1 | INSECTICIDAL COMBINATIONS | Vestaron Corporation (US) | 2023-03-08 | — | — | EP | disclosed |