Azadiradione

Azadiradione

SCHEMBL29398035

CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@]3(C)C(=CC(=O)[C@H]3c3ccoc3)[C@@]21C

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 9/20 0.77
▸ SLCO1B3 Q9NPD5 7/20 0.77
▸ SLCO1B1 Q9Y6L6 7/20 0.77
▸ SMN1; SMN2 Q16637 6/20 0.77
▸ TP53 P04637 4/20 0.77
▸ TDP1 Q9NUW8 2/20 0.77
▸ HSD11B1 P28845 1/20 0.64
▸ MIF P14174 1/20 0.61
▸ USP2 O75604 6/20 0.57
▸ MAPT P10636 4/20 0.57
▸ ALDH1A1 P00352 3/20 0.57
▸ LMNA P02545 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ GSK3B P49841 1/20 0.55
▸ HPGD P15428 1/20 0.52
▸ MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azadiradione SCHEMBL17301643 1.00 CYP3A4 (0.77) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
Azadiradione SCHEMBL15941112 1.00 CYP3A4 (0.77) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
Azadiradione SCHEMBL19588462 1.00 CYP3A4 (0.77) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL17368654 0.92 CYP3A4 (0.74) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL30278964 0.90 CYP3A4 (0.62) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL9973669 0.87 CYP3A4 (1.00) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL20639350 0.87 CYP3A4 (1.00) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL598727 0.87 CYP3A4 (1.00) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL14197006 0.87 CYP3A4 (1.00) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53
SCHEMBL10019478 0.87 CYP3A4 (1.00) CYP3A4SLCO1B3SLCO1B1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076366-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS 0903608 B C LTD (CA) 2026-03-19 — — US claimed
US-20240041038-A1 INSECTICIDAL COMBINATIONS Vestaron Corporation (US) 2024-02-08 — — US claimed
WO-2023154183-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY (US) 2023-08-17 — — WO claimed
EP-4142498-A1 INSECTICIDAL COMBINATIONS Vestaron Corporation (US) 2023-03-08 — — EP claimed
US-20220272987-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY H (US) 2022-09-01 — — US claimed
US-20260076366-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS 0903608 B C LTD (CA) 2026-03-19 — — US disclosed
US-12568947-B2 Compositions, devices and methods for control of pests using vapor activity 0903608 B.C. LTD. (CA) 2026-03-10 — — US disclosed
US-12501898-B2 Synergistic pesticidal compositions and methods for delivery of active ingredients 0903608 B.C. LTD. (CA) 2025-12-23 — — US disclosed
US-12336526-B2 Compositions, devices and methods for plant health and pest control using vapor activity 0903608 B.C. LTD. (CA) 2025-06-24 — — US disclosed
US-20240389581-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF INSECTICIDAL ACTIVE INGREDIENTS TERRAMERA, INC. (CA) 2024-11-28 — — US disclosed
US-20240074434-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY HANSON (US) 2024-03-07 — — US disclosed
US-20240065262-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY HANSON (US) 2024-02-29 — — US disclosed
WO-2022231458-A1 USE OF A TOOTHPASTE TO REDUCE STATE AND TRAIT ANXIETY "СКАЙЛАБ AT" 2022-11-03 — — WO disclosed
US-11470843-B2 Tissue bonding insect repellent Hour 72 (US) 2022-10-18 — — US disclosed
US-20220272987-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY H (US) 2022-09-01 — — US disclosed
US-20220233624-A9 ANTI-CANCER AND ANTI-PROLIFERATIVE COMPOSITIONS, AND METHODS FOR THEIR USE IN TREATING CANCER NATREON, INC. (US) 2022-07-28 — — US disclosed
EP-3466930-B1 REDUCED SODIUM FOOD PRODUCT GEN MILLS INC (US) 2022-07-20 — — EP disclosed
US-11299700-B1 Bioreactor containers and methods of growing hairy roots using the same ACEQUIA BIOTECHNOLOGY, LLC (US) 2022-04-12 — — US disclosed
WO-2022040321-A1 PROTECTION AGAINST CORONAVIRUS INFECTION BY EXTRACTS AND EXTRACT COMPONENTS NATREON, INC. (US) 2022-02-24 — — WO disclosed
US-20220054575-A1 PROTECTION AGAINST CORONAVIRUS INFECTION BY EXTRACTS AND EXTRACT COMPONENTS NATREON, INC. (US) 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076366-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS TACR3, GSTO1, TIAL1 CYP3A4 1293/4885SLCO1B3 1530/4885SLCO1B1 2245/4885
US-12568947-B2 Compositions, devices and methods for control of pests using vapor activity TYR, PNMT, PNN CYP3A4 930/4885SLCO1B3 4599/4885SLCO1B1 4618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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