SCHEMBL30279293

SCHEMBL30279293

CC(C)C[C@@H](C(=O)O)N(C)C(=O)[C@H](COC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.45
TP53 P04637 3/20 0.45
CTSL P07711 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
CASP3 P42574 1/20 0.41
MDM2 Q00987 2/20 0.41
PTPN1 P18031 2/20 0.41
TLR2 O60603 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670446 0.84 CASP3 (0.47) MDM4TP53CASP3MDM2
SCHEMBL29355082 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL29624621 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL30802551 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL29367497 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL119575 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL119565 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL598209 0.84 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
Fluoride SCHEMBL7155195 0.83 MDM4 (0.55) MDM4TP53CASP3MDM2TLR2
SCHEMBL13380598 0.82 MDM4 (0.45) MDM4TP53CASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-21 US disclosed
EP-4144747-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES NGLY1, VIP, DNPEP MDM4 794/4885TP53 410/4885CTSL 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.