Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 8/20 | 0.47 |
| ▸ | ADH1C | P00326 | 5/20 | 0.47 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660578 | 1.00 | ADH1A (0.47) | ADH1AADH1CADH1BL3MBTL1MEN1 | |
| SCHEMBL9660966 | 1.00 | ADH1A (0.47) | ADH1AADH1CADH1BL3MBTL1MEN1 | |
| SCHEMBL967214 | 0.98 | ADH1A (0.43) | ADH1AADH1CADH1BL3MBTL1MEN1 | |
| SCHEMBL969251 | 0.95 | — | — | |
| SCHEMBL967293 | 0.88 | — | — | |
| SCHEMBL304405 | 0.83 | ADH1A (0.50) | ADH1AADH1CADH1B | |
| SCHEMBL9660549 | 0.83 | ADH1A (0.50) | ADH1AADH1CADH1B | |
| SCHEMBL9660999 | 0.83 | ADH1A (0.50) | ADH1AADH1CADH1B | |
| SCHEMBL3024929 | 0.80 | ADH1A (0.48) | ADH1AADH1C | |
| SCHEMBL9658873 | 0.79 | ADH1A (0.43) | ADH1AADH1CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | claimed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| CN-1402613-A | Method for increasing yield of crops | BAYER AGROCHEM KK (JP) | 2003-03-12 | — | — | CN | claimed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | claimed |
| WO-2001039595-A2 | METHOD FOR INCREASING THE YIELD OF CROPS | NIHON BAYER AGROCHEM K.K. (DE) | 2001-06-07 | — | — | WO | claimed |
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1999021860-B1 | PHENANTHROLINE DERIVATIVES | FIBROGEN INC (US) | 1999-08-05 | — | — | WO | claimed |
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | claimed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | claimed |
| US-20200129458-A1 | COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS | AJINOMOTO CO., INC. (JP) | 2020-04-30 | — | — | US | disclosed |
| EP-3438091-A1 | COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS | AJINOMOTO CO., INC. (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-20190022039-A1 | COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS | AJINOMOTO CO., INC. (JP) | 2019-01-24 | — | — | US | disclosed |
| EP-2318355-B1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-9255070-B2 | Method of deuteration using mixed catalyst | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2016-02-09 | — | — | US | disclosed |
| US-4091220-A | RESPIRATORY TRACK FLUID SECRETION STIMULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4055714-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4045427-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4045426-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4042773-A | REACTION WITH POLYMERS | PENNWALT CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-3956269-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200129458-A1 | COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS | GLP1R, GPR119, GIPR | ADH1A 1538/4885ADH1C 987/4885ADH1B 2438/4885 |
| US-20190022039-A1 | COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS | GLP1R, GPR119, GIPR | ADH1A 1538/4885ADH1C 987/4885ADH1B 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.