Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340669 | 0.84 | KDM4E (0.53) | SLC22A12SMN1; SMN2MAPTALDH1A1PDE10A | |
| SCHEMBL3468178 | 0.81 | ADORA2A (0.50) | SLC22A12MAPTALDH1A1PDE10AKDM4E | |
| SCHEMBL10419666 | 0.81 | KDM4E (0.50) | SLC22A12SMN1; SMN2MAPTALDH1A1PDE10A | |
| SCHEMBL25245831 | 0.80 | SMN1; SMN2 (0.59) | SLC22A12SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL25570920 | 0.80 | NPSR1 (0.50) | SLC22A12SMN1; SMN2ALDH1A1PDE10AKDM4E | |
| SCHEMBL17859440 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL30423331 | 0.78 | SLC22A12 (0.43) | SLC22A12SMN1; SMN2PDE10AKDM4ELMNA | |
| SCHEMBL25215276 | 0.78 | SLC22A12 (0.43) | SLC22A12SMN1; SMN2PDE10AKDM4ELMNA | |
| SCHEMBL28179746 | 0.77 | SLC22A12 (0.49) | SLC22A12SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL25245065 | 0.77 | GAA (0.50) | SLC22A12SMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605237-B | Preparation method and application of fluoroalkyl ketone compound | 武汉大学 | 2023-02-24 | — | — | CN | disclosed |