Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215276 | 1.00 | SLC22A12 (0.43) | SLC22A12MEN1KMT2APDE10AHCRTR1 | |
| SCHEMBL30280438 | 0.78 | SLC22A12 (0.49) | SLC22A12PDE10AHCRTR1HCRTR2KDM4E | |
| SCHEMBL3468178 | 0.78 | ADORA2A (0.50) | SLC22A12MEN1KMT2APDE10AKDM4E | |
| SCHEMBL1340669 | 0.77 | KDM4E (0.53) | SLC22A12PDE10AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL25256041 | 0.76 | ALDH1A1 (0.37) | SLC22A12MEN1KMT2APDE10AHCRTR1 | |
| SCHEMBL30423687 | 0.76 | ALDH1A1 (0.37) | SLC22A12MEN1KMT2APDE10AHCRTR1 | |
| SCHEMBL10419666 | 0.74 | KDM4E (0.50) | SLC22A12PDE10AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL25245831 | 0.73 | SMN1; SMN2 (0.59) | SLC22A12MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL25245065 | 0.73 | GAA (0.50) | SLC22A12MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL25570920 | 0.73 | NPSR1 (0.50) | SLC22A12PDE10AKDM4ESMN1; SMN2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | claimed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |