Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280475 | 1.00 | ENPP3 (0.41) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL25262262 | 0.88 | ENPP3 (0.42) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL7513541 | 0.88 | PTGDR2 (0.43) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL20502449 | 0.84 | ENPP3 (0.40) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL30280403 | 0.84 | ENPP3 (0.40) | ENPP3ENPP1PTGDR2LMNAALDH3A1 | |
| SCHEMBL20502619 | 0.83 | AGTR1 (0.42) | ENPP3ENPP1PTGDR2LMNAALDH3A1 | |
| SCHEMBL30280425 | 0.83 | ENPP3 (0.39) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL20502546 | 0.81 | PTGDR2 (0.43) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL23101603 | 0.81 | PTGDR2 (0.41) | ENPP3ENPP1PTGDR2ABL1BCR | |
| SCHEMBL30280408 | 0.81 | ENPP3 (0.38) | ENPP3ENPP1PTGDR2LMNAALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064218-A1 | TYRO3 INHIBITORS | Halia Therapeutics, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |