Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028047 | 1.00 | TDO2 (0.31) | TDO2RIPK1 | |
| SCHEMBL3227321 | 0.90 | TDO2 (0.33) | TDO2RIPK1 | |
| SCHEMBL1277661 | 0.87 | TDO2 (0.34) | TDO2RIPK1 | |
| SCHEMBL1277657 | 0.87 | TDO2 (0.34) | TDO2RIPK1 | |
| SCHEMBL1278053 | 0.85 | TDO2 (0.31) | TDO2RIPK1 | |
| SCHEMBL1278049 | 0.85 | TDO2 (0.31) | TDO2RIPK1 | |
| SCHEMBL1278122 | 0.85 | TDO2 (0.33) | TDO2RIPK1 | |
| SCHEMBL1278121 | 0.85 | TDO2 (0.33) | TDO2RIPK1 | |
| SCHEMBL1277757 | 0.85 | DNM2 (0.31) | TDO2 | |
| SCHEMBL1277756 | 0.85 | DNM2 (0.31) | TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178869-B1 | INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG LIFE SCIENCES LTD (KR) | 2013-06-12 | — | — | EP | claimed |
| US-20100210647-A1 | INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210647-A1 | INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | IDO1, IDO2, TNF | TDO2 27/4885RIPK1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.