Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281015 | 0.88 | FASN (0.34) | FASN | |
| SCHEMBL12488288 | 0.82 | FASN (0.42) | PDK2PDK4FASN | |
| SCHEMBL30280872 | 0.78 | PDK2 (0.39) | PDK2PDK4SPR | |
| SCHEMBL30280756 | 0.72 | PDK2 (0.35) | PDK2PDK4 | |
| SCHEMBL30281129 | 0.72 | FASN (0.43) | PDK2PDK4FASNSPRKDM4E | |
| SCHEMBL30281061 | 0.71 | FASN (0.46) | PDK2PDK4FASNSPR | |
| SCHEMBL30280967 | 0.70 | PDK2 (0.36) | PDK2PDK4KDM4E | |
| SCHEMBL30281153 | 0.69 | LMNA (0.31) | — | |
| SCHEMBL30280964 | 0.69 | JAK1 (0.35) | PDK2PDK4FASNKDM4E | |
| SCHEMBL12488258 | 0.67 | FASN (0.42) | PDK2PDK4FASNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |