Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 3/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26800328 | 0.95 | KDM4E (0.54) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL24792464 | 0.94 | KDM4E (0.58) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL27485647 | 0.88 | KDM4E (0.47) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL15712821 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL26116353 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL15712225 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL12488998 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL28721789 | 0.83 | ACMSD (0.55) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL30409796 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL2403289 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EGAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |