Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529118 | 1.00 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1LMNAKAT6AHTT | |
| SCHEMBL4443811 | 0.88 | MRGPRX4 (0.50) | MRGPRX4ALDH1A1LMNAHTTTSHR | |
| SCHEMBL2619294 | 0.88 | MRGPRX4 (0.50) | MRGPRX4ALDH1A1LMNAHTTTSHR | |
| SCHEMBL30469438 | 0.86 | ALDH1A1 (0.51) | MRGPRX4ALDH1A1LMNAHTTTSHR | |
| SCHEMBL1052962 | 0.86 | ALDH1A1 (0.51) | MRGPRX4ALDH1A1LMNAHTTTSHR | |
| SCHEMBL1401560 | 0.85 | TSHR (0.57) | ALDH1A1LMNAHTTTSHRSLC6A4 | |
| SCHEMBL22702311 | 0.84 | TSHR (0.61) | MRGPRX4ALDH1A1LMNAKAT6AHTT | |
| SCHEMBL23169118 | 0.84 | CA12 (0.42) | ALDH1A1LMNAHTTTSHRSLC6A4 | |
| SCHEMBL4447482 | 0.83 | ALDH1A1 (0.49) | MRGPRX4ALDH1A1LMNATSHRSLC6A4 | |
| SCHEMBL27873404 | 0.83 | ALDH1A1 (0.49) | MRGPRX4ALDH1A1LMNAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |