Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054506 | 0.89 | LOXL2 (0.52) | ALDH1A1LMNAHMGB1MRGPRX4HSD17B10 | |
| SCHEMBL4443811 | 0.89 | MRGPRX4 (0.50) | ALDH1A1LMNAMRGPRX4CFTRHSD17B10 | |
| SCHEMBL4447946 | 0.86 | GAA (0.42) | ALDH1A1LMNACFTRHSD17B10KMT2A | |
| SCHEMBL27873404 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAMRGPRX4CFTRHSD17B10 | |
| SCHEMBL4739142 | 0.83 | ALDH1A1 (0.68) | ALDH1A1LMNAHMGB1CFTRHSD17B10 | |
| SCHEMBL24529118 | 0.83 | MRGPRX4 (0.51) | ALDH1A1LMNAMRGPRX4CFTRHSD17B10 | |
| SCHEMBL30280757 | 0.83 | MRGPRX4 (0.51) | ALDH1A1LMNAMRGPRX4CFTRHSD17B10 | |
| Hydrochloric Acid SCHEMBL4443950 | 0.82 | ALDH1A1 (0.66) | ALDH1A1LMNAHMGB1CFTRHSD17B10 | |
| SCHEMBL2619294 | 0.82 | MRGPRX4 (0.50) | ALDH1A1LMNAMRGPRX4CFTRHSD17B10 | |
| SCHEMBL1052962 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAMRGPRX4CFTRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, ZC3HAV1, EIF2AK2 | ALDH1A1 2676/4885LMNA 2620/4885HMGB1 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.