SCHEMBL302808

SCHEMBL302808

Pc1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.55
ALDH1A1 P00352 8/20 0.53
HSD17B10 Q99714 5/20 0.53
CYP2A6 P11509 4/20 0.53
TSHR P16473 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
HPGD P15428 3/20 0.48
CYP3A4 P08684 2/20 0.48
KEAP1 Q14145 1/20 0.48
HPRT1 P00492 2/20 0.48
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
THRB P10828 1/20 0.43
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL15845281 0.97 CYP1A2 (0.52) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
Selenic Acid SCHEMBL28804100 0.86 CYP1A2 (0.48) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL941402 0.85 HPRT1 (0.67) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL365419 0.79 ALDH1A1 (0.43) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
Tromethamine SCHEMBL6032871 0.79 CYP1A2 (0.42) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
Water SCHEMBL7645621 0.78 ALDH1A1 (0.42) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL939546 0.76 ALDH1A1 (0.45) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL30544433 0.76 ALDH1A1 (0.45) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL19618737 0.75 HPRT1 (0.38) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1323080 0.74 ALDH1A1 (0.40) CYP1A2ALDH1A1HSD17B10TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 786 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777153-A 20 (S) -10, 11-difluoro methylenedioxy camptothecine derivative and preparation method and application thereof 浙江工业大学 2024-03-29 CN claimed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-117327007-A VT107 preparation method 上海陶术生物科技有限公司 2024-01-02 CN claimed
CN-114478632-B Spirodidihydrobenzosilole biphosphines compound, preparation method and application thereof 中国科学院上海有机化学研究所 2023-10-27 CN claimed
CN-116924870-A Synthesis method of 1-substituted phenanthrene compound 西北师范大学 2023-10-24 CN claimed
CN-115043847-B Preparation method of 10H-indolo [1,2-a ] indol-10-one compound 西北师范大学 2023-05-26 CN claimed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN claimed
CN-115536817-A Naphthyl-substituted asymmetric metal catalyst and preparation method and application thereof 武汉工程大学 2022-12-30 CN claimed
CN-115043847-A Preparation method of 10H-indolo [1,2-a ] indol-10-one compound 西北师范大学 2022-09-13 CN claimed
CN-114656347-A Synthesis method of palladium-catalyzed C-1 deuterated aromatic aldehyde 南京林业大学 2022-06-24 CN claimed
CN-1208360-C In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO (JP) 2005-06-29 CN claimed
CN-1583174-A Long-term injection containing ethylcellulose and fatty acid ester WANG YUWAN (CN) 2005-02-23 CN claimed
CN-1565470-A Antiparasitic medicine long-acting injection containing WANG YUWAN (CN) 2005-01-19 CN claimed
CN-1444925-A Long acting injection containing ethyl cellulose for animal WANG YUWAN (CN) 2003-10-01 CN claimed
CN-1111519-C Alpha-aromatic ethanol oxonation prepares the method for alpha-aryl propionic acid and ester thereof LANZHOU INST CHEMICOPHYSICS (CN) 2003-06-18 CN claimed
CN-1386507-A Compound antiparasitic medicine for fish or full-value feed containing antiparasitic medicine WANG YUWAN (CN) 2002-12-25 CN claimed
CN-1289759-A Process for preparing alpha-arylpropionic acid and its salts by oxonation of alpha-arylalcohol LANZHOU INST CHEMICOPHYSICS (CN) 2001-04-04 CN claimed
CN-1059890-C Method of synthetizing alpha-aryl propionic acid by carbonyl process LANZHOU CHEM PHYS INST (CN) 2000-12-27 CN claimed
CN-1221728-A Method of synthetizing alpha-aryl propionic acid by carbonyl process LANZHOU CHEM PHYS INST (CN) 1999-07-07 CN claimed
US-4152498-A CORROSION RESISTANCE, HIGH MELT STABILITY, AGING AND HEAT RESISTANCE DEMIDOVA VALENTINA M (SU) 1979-05-01 US claimed