Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7645621 | 0.98 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL9927300 | 0.85 | CRHBP (0.36) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL25302086 | 0.84 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL27953 | 0.84 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL29350007 | 0.84 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL17836548 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL18174178 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| Ammonia Solution, Strong SCHEMBL3156160 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| Bromide SCHEMBL7106161 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL6077039 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024477-A | Preparation method of aliphatic chain substituted biphenyl type or phenyl pyrrole type chiral monophosphine ligand | 南京大学 | 2023-11-10 | — | — | CN | disclosed |
| EP-3461556-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | AbbVie Ireland Unlimited Company (IE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2593226-B1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE IRELAND UNLIMITED CO (IE) | 2018-11-14 | — | — | EP | disclosed |
| CN-104974822-B | A kind of preparation method of anti-pressure and abrasion-proof lubricant | 鲁克（中国）润滑油有限公司 | 2018-01-30 | — | — | CN | disclosed |
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160263566-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE INC. | 2016-09-15 | — | — | US | disclosed |
| US-20160263566-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE INC. | 2016-09-15 | — | — | US | disclosed |
| US-20160263566-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE INC. | 2016-09-15 | — | — | US | disclosed |
| EP-2593226-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | Abbvie Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| CN-103097027-A | Phosphine ligands for catalytic reactions | ABBVIE INC | 2013-05-08 | — | — | CN | disclosed |
| US-20120022252-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120022252-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120022252-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |
| EP-1670860-B1 | FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY | ALBEMARLE CORP (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1670860-A1 | FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY | ALBEMARLE CORPORATION (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005040277-A1 | FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY | ALBEMARLE CORPORATION (US) | 2005-05-06 | — | — | WO | disclosed |
| US-20050075024-A1 | Flame retardant epoxy prepregs, laminates, and printed wiring boards of enhanced thermal stability | ALBEMARLE CORPORATION | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263566-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | PHOSPHO1, PLCG2, PPIP5K2 | ALDH1A1 4611/4885TSHR 3889/4885HSD17B10 3389/4885 |
| US-20120022252-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | PHOSPHO1, PPIP5K2, ITPA | ALDH1A1 4364/4885TSHR 2675/4885HSD17B10 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.