SCHEMBL17239556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12488367	0.86	CFTR (0.43)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL2849661	0.85	CFTR (0.45)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL14590043	0.85	GAA (0.47)	GAAABL1MEN1KMT2ALMNA
	SCHEMBL30280800	0.83	CFTR (0.46)	CFTRGAAKMT2ALMNANR4A2
	SCHEMBL7863946	0.83	GAA (0.50)	GAAABL1MEN1KMT2ALMNA
	SCHEMBL25455691	0.83	CFTR (0.46)	CFTRGAAABL1LMNANR4A2
	SCHEMBL1920431	0.83	CFTR (0.46)	CFTRGAAKMT2ALMNANR4A2
	SCHEMBL7948445	0.82	NR4A2 (0.46)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL7082612	0.81	GAA (0.46)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL8331820	0.81	GAA (0.53)	CFTRGAAABL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.