Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | USP14 | P54578 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280955 | 0.93 | GPR119 (0.46) | GPR119ARJAK2JAK3PTK2 | |
| SCHEMBL21001077 | 0.89 | GPR119 (0.52) | GPR119ARJAK2JAK3PTK2 | |
| SCHEMBL30280984 | 0.88 | GPR119 (0.47) | GPR119ARJAK2JAK3PTK2 | |
| SCHEMBL31421008 | 0.85 | GPR119 (0.51) | GPR119ARRIPK1 | |
| SCHEMBL29148949 | 0.84 | GPR119 (0.44) | GPR119ARJAK2JAK3PTK2 | |
| SCHEMBL12979900 | 0.84 | MEN1 (0.43) | CHRM2CHRM1CHRM3NR1H2NR1H3 | |
| SCHEMBL2708229 | 0.84 | MEN1 (0.43) | CHRM2CHRM1CHRM3NR1H2NR1H3 | |
| SCHEMBL28070981 | 0.84 | NR1H2 (0.50) | CHRM2CHRM1CHRM3NR1H2NR1H3 | |
| SCHEMBL2708227 | 0.84 | MEN1 (0.43) | CHRM2CHRM1CHRM3NR1H2NR1H3 | |
| SCHEMBL28070953 | 0.84 | GPR119 (0.50) | GPR119ARJAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |