SCHEMBL3028100

SCHEMBL3028100

CC=Cc1ccc(N(C)C)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.67
RELA Q04206 1/20 0.64
MAPT P10636 6/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
CASP1 P29466 2/20 0.59
HBB P68871 2/20 0.59
ALOX15 P16050 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
HSD17B3 P37058 1/20 0.57
KDM4E B2RXH2 1/20 0.57
CYP2A6 P11509 1/20 0.56
CYP2A13 Q16696 1/20 0.56
ALDH1A1 P00352 3/20 0.55
LMNA P02545 2/20 0.55
GAA P10253 1/20 0.55
BRCA1 P38398 1/20 0.55
CASP7 P55210 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24891034 1.00 APP (0.67) APPRELAMAPTMEN1KMT2A
SCHEMBL10603693 1.00 APP (0.67) APPRELAMAPTMEN1KMT2A
SCHEMBL10216130 0.88 ALDH1A1 (0.57) APPRELAMAPTMEN1KMT2A
SCHEMBL7915381 0.87 RELA (0.81) APPRELAMAPTMEN1KMT2A
SCHEMBL3025040 0.87 RELA (0.81) APPRELAMAPTMEN1KMT2A
SCHEMBL1714446 0.87 RELA (0.81) APPRELAMAPTMEN1KMT2A
SCHEMBL1714449 0.87 RELA (0.81) APPRELAMAPTMEN1KMT2A
SCHEMBL13467434 0.87 RELA (0.81) APPRELAMAPTMEN1KMT2A
SCHEMBL29389358 0.84 RELA (0.77) APPRELAMAPTMEN1KMT2A
SCHEMBL12267732 0.84 APP (0.79) APPRELAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515912-B1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NAT RECH SCIENT (FR) 2020-10-14 EP disclosed
US-20130128339-A1 PHOTOREFRACTIVE COMPOSITION RESPONSIVE TO MULTIPLE LASER WAVELENGTHS ACROSS THE VISIBLE LIGHT SPECTRUM NITTO DENKO CORPORATION (JP) 2013-05-23 US disclosed
US-7812096-B2 Modification method of polymer THE YOKOHAMA RUBBER CO., LTD. (JP) 2010-10-12 US disclosed
US-7785735-B2 Microporous composite membrane and its producing method and use TONEN CHEMICAL CORPORATION (JP) 2010-08-31 US disclosed
EP-1693408-B1 MICROPOROUS COMPOSITE FILM, PROCESS FOR PRODUCING THE SAME, AND USE TONEN SEKIYUKAGAKU KK (JP) 2010-04-14 EP disclosed
US-20070128512-A1 Microporous composite membrane and its producing method and use TORAY INDUSTRIES, INC. (JP) 2007-06-07 US disclosed
EP-1693408-A1 MICROPOROUS COMPOSITE FILM, PROCESS FOR PRODUCING THE SAME, AND USE Tonen Chemical Corporation (JP) 2006-08-23 EP disclosed
US-20060160956-A1 Modification method of polymer THE YOKOHAMA RUBBER CO., LTD. 2006-07-20 US disclosed
EP-0656893-B1 PHOTOCHROMIC OXAZINE COMPOUNDS RODENSTOCK OPTIK G (DE) 2001-12-12 EP disclosed
EP-0350069-B1 METHOD FOR OXIDIZING UNSATURATED AROMATIC COMPOUNDS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
US-4967009-A REACTING UNSATURATED AROMATIC COMPOUNDS WITH AROMATIC IODOSYL COMPOUNDS TO YIELD AROMATIC ALDEHYDES OR KETONES NIPPON PETROCHEMICALS CO., LTD. (JP) 1990-10-30 US disclosed
EP-0350069-A2 Method for oxidizing unsaturated aromatic compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-01-10 EP disclosed
EP-0104863-B1 LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed
US-4474868-A ORGANIC PEROXIDE AND COMPOUND CONTAINING CATIONIC OXYGEN, SULFUR OXYGEN,SULFUR OR SELENIUM NIPPON OIL AND FATS CO., LTD. (JP) 1984-10-02 US disclosed
US-4119776-A Vinyl phthalide color formers NCR CORPORATION (US) 1978-10-10 US disclosed
US-4022771-A RECORD MATERIALS AND MARKING SYSTEMS NCR CORPORATION (US) 1977-05-10 US disclosed