Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.63 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349455 | 0.85 | SMN1; SMN2 (0.67) | ALDH1A1KMT2AHPGDTP53GAA | |
| Hydrochloric Acid SCHEMBL17559454 | 0.83 | SMN1; SMN2 (0.65) | ALDH1A1KMT2AHPGDTP53GAA | |
| Oxirane SCHEMBL15106942 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KMT2AHPGDHSD17B10KDM4E | |
| SCHEMBL5004375 | 0.75 | KDM4E (0.49) | MGLLALDH1A1HPGDTP53KDM4E | |
| SCHEMBL325422 | 0.75 | NPC1 (0.70) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL29410870 | 0.75 | NPC1 (0.70) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL7121916 | 0.74 | SMN1; SMN2 (0.77) | ALDH1A1KMT2AHPGDTP53GAA | |
| Bromide SCHEMBL6256143 | 0.73 | NPC1 (0.68) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL3226592 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL31264013 | 0.72 | PARP1 (0.38) | ALDH1A1HPGDHSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |