SCHEMBL5349455

SCHEMBL5349455

NC(=O)c1ccccc1C(=O)N1CCOCC1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.67
GAA P10253 2/20 0.67
ALDH1A1 P00352 5/20 0.60
TSHR P16473 3/20 0.56
NPSR1 Q6W5P4 1/20 0.56
TP53 P04637 1/20 0.56
KMT2A Q03164 3/20 0.55
HTT P42858 2/20 0.55
MEN1 O00255 2/20 0.53
USP2 O75604 1/20 0.53
HPGD P15428 1/20 0.53
PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17559454 0.98 SMN1; SMN2 (0.65) SMN1; SMN2GAAALDH1A1TSHRNPSR1
SCHEMBL7121916 0.91 SMN1; SMN2 (0.77) SMN1; SMN2GAAALDH1A1TSHRNPSR1
SCHEMBL20567427 0.87 ALDH1A1 (0.61) SMN1; SMN2GAAALDH1A1TSHRKMT2A
SCHEMBL30281137 0.85 MGLL (0.63) SMN1; SMN2GAAALDH1A1NPSR1TP53
SCHEMBL20267430 0.84 GAA (0.73) SMN1; SMN2GAAALDH1A1TSHRNPSR1
SCHEMBL3226592 0.84 ALDH1A1 (0.55) SMN1; SMN2GAAALDH1A1TSHRNPSR1
SCHEMBL6474889 0.84 TSHR (0.59) SMN1; SMN2GAAALDH1A1TSHRKMT2A
(2-Aminophenyl)(Morpholino)Methanone SCHEMBL11446442 0.83 GAA (0.62) SMN1; SMN2GAAALDH1A1TSHRNPSR1
(2-Aminophenyl)(Morpholino)Methanone SCHEMBL30988542 0.83 GAA (0.62) SMN1; SMN2GAAALDH1A1TSHRNPSR1
SCHEMBL1583125 0.82 SMN1; SMN2 (0.59) SMN1; SMN2GAAALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676600-A1 PROTEIN KINASE INHIBITORS AND USES THEREOF Deliver Therapeutics, Inc. (US) 2026-01-14 EP disclosed
WO-2024186579-A1 PROTEIN KINASE INHIBITORS AND USES THEREOF DELIVER THERAPEUTICS, INC. (US) 2024-09-12 WO disclosed
US-20070213407-A1 Compounds to treat Alzheimer's disease ELAN PHARMACEUTICALS AND PHARMACIA & UPJOHN COMPANY LLC 2007-09-13 US disclosed
US-7214715-B2 Compounds to treat Alzheimer's disease PHARMACIA & UPJOHN (US) 2007-05-08 US disclosed
EP-1025095-A1 SUBSTITUTED CHROMAN DERIVATIVES AstraZeneca AB (SE) 2000-08-09 EP disclosed
WO-1999014212-A1 SUBSTITUTED CHROMAN DERIVATIVES ASTRAZENECA AB (SE) 1999-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213407-A1 Compounds to treat Alzheimer's disease PSEN2, PSEN1, CHAT SMN1; SMN2 539/4885GAA 57/4885ALDH1A1 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.