Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23990516 | 0.85 | ALDH1A1 (0.31) | — | |
| SCHEMBL28976531 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL12410702 | 0.82 | PIK3CA (0.39) | PIK3CAACHEPIK3CDPIK3CBPIK3CG | |
| Lithium Ion SCHEMBL30281195 | 0.82 | — | — | |
| SCHEMBL23989804 | 0.81 | POLB (0.32) | — | |
| SCHEMBL23990518 | 0.80 | — | — | |
| SCHEMBL24770482 | 0.80 | — | — | |
| SCHEMBL30281283 | 0.79 | ACHE (0.33) | PIK3CAACHEPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30999737 | 0.73 | ALDH1A1 (0.40) | PIK3CD | |
| SCHEMBL30420636 | 0.73 | ALDH1A1 (0.40) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |