Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989860 | 0.86 | MKNK2 (0.31) | MKNK2 | |
| SCHEMBL30281343 | 0.79 | PARP10 (0.40) | MKNK2 | |
| SCHEMBL30281297 | 0.75 | MKNK2 (0.32) | CNR2MKNK2 | |
| SCHEMBL30281336 | 0.73 | NNMT (0.40) | MKNK2 | |
| SCHEMBL30281245 | 0.72 | IRAK4 (0.45) | MKNK2MAP3K7TAB1 | |
| SCHEMBL30616808 | 0.72 | POLB (0.32) | — | |
| SCHEMBL23990406 | 0.71 | CA12 (0.36) | CNR2MKNK2 | |
| SCHEMBL2528993 | 0.70 | RAB9A (0.37) | CNR2MKNK2 | |
| SCHEMBL30616810 | 0.69 | — | — | |
| SCHEMBL24768401 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |