Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24770460 | 0.79 | POLB (0.38) | HDAC1HDAC6 | |
| SCHEMBL12498978 | 0.77 | PDE4B (0.33) | PIK3CATGFBR1 | |
| SCHEMBL30281298 | 0.76 | — | — | |
| SCHEMBL16490477 | 0.76 | PIK3CA (0.31) | PIK3CA | |
| SCHEMBL30281208 | 0.76 | PIK3CA (0.41) | PIK3CA | |
| SCHEMBL30281273 | 0.75 | CNR1 (0.32) | TGFBR1 | |
| SCHEMBL3473167 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL30281146 | 0.73 | PIK3CA (0.33) | PIK3CATGFBR1TGFBR2 | |
| SCHEMBL30209669 | 0.71 | SIRT2 (0.36) | HDAC1PIK3CA | |
| SCHEMBL28976350 | 0.71 | ATM (0.31) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |