Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281208 | 0.87 | PIK3CA (0.41) | PIK3CAPIK3CDPIK3CGATM | |
| SCHEMBL25745169 | 0.85 | ATM (0.33) | ATM | |
| Lithium Ion SCHEMBL30281281 | 0.83 | — | — | |
| SCHEMBL24770485 | 0.81 | NPC1 (0.35) | ALDH1A1 | |
| SCHEMBL24769599 | 0.80 | — | — | |
| SCHEMBL12498978 | 0.78 | PDE4B (0.33) | PIK3CAALDH1A1TGFBR1PIK3CDPIK3CG | |
| SCHEMBL30281196 | 0.74 | ABL1 (0.32) | PIK3CA | |
| SCHEMBL30281185 | 0.73 | HDAC1 (0.31) | PIK3CATGFBR1TGFBR2 | |
| SCHEMBL30281273 | 0.72 | CNR1 (0.32) | TGFBR1 | |
| SCHEMBL12410714 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNATGFBR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |