Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349618 | 1.00 | FOLH1 (0.53) | FOLH1ALDH1A1ALOX15TSHRTP53 | |
| SCHEMBL9954558 | 0.83 | FOLH1 (0.57) | FOLH1ALDH1A1ALOX15TSHRTP53 | |
| SCHEMBL27517607 | 0.83 | MRGPRX4 (0.49) | FOLH1ALDH1A1ALOX15TSHRHMGB1 | |
| SCHEMBL19565887 | 0.82 | HCRTR2 (0.44) | ALDH1A1KDM4ESMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL363265 | 0.82 | KDM4E (0.45) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9243615 | 0.82 | ALDH1A1 (0.48) | FOLH1ALDH1A1ALOX15GAAHCRTR1 | |
| SCHEMBL27948149 | 0.82 | MRGPRX4 (0.45) | FOLH1ALDH1A1ALOX15TSHRHTT | |
| SCHEMBL11881450 | 0.82 | FOLH1 (0.55) | FOLH1ALDH1A1ALOX15TSHRTP53 | |
| SCHEMBL24072616 | 0.81 | FOLH1 (0.59) | FOLH1ALDH1A1ALOX15TSHRTP53 | |
| Hydrochloric Acid SCHEMBL28047477 | 0.81 | KDM4E (0.44) | ALDH1A1TSHRKDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |