Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | NSD2 | O96028 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | THRB | P10828 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | GNG2 | P59768 | 5/20 | 0.65 |
| ▸ | GNB1 | P62873 | 5/20 | 0.65 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.61 |
| ▸ | P2RY4 | P51582 | 9/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333865 | 0.99 | ALDH1A1 (0.79) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL30205040 | 0.98 | ALDH1A1 (0.77) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL11603300 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL8630004 | 0.87 | GNG2 (0.66) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL13214108 | 0.87 | GNG2 (0.64) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL3030977 | 0.87 | GNG2 (0.76) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| Acid Blue 129 SCHEMBL29425182 | 0.86 | P2RY1 (1.00) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| Acid Blue 129 SCHEMBL2854160 | 0.86 | P2RY1 (1.00) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL13214098 | 0.86 | GNG2 (0.78) | ALDH1A1HPGDMAPK1MEN1NSD2 | |
| SCHEMBL28444449 | 0.86 | P2RY4 (0.74) | ALDH1A1HPGDMAPK1MEN1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129653-B1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2010-08-19 | — | — | US | disclosed |
| EP-1967513-A1 | Novel P2Y12 receptor antagonists | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2008-09-10 | — | — | EP | disclosed |
| US-4289496-A | LOW LIQUID TO MATERIAL RATIO RESULTING IN UNIFORMITY OF FINISHING | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | P2RY12, P2RY11, P2RY13 | ALDH1A1 2377/4885HPGD 978/4885MAPK1 1228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.