SCHEMBL30284178

SCHEMBL30284178

O=C(c1ccccc1)c1ccc(-c2ccc3c4c(ccc3c2)OC(c2ccccc2)(c2ccccc2)C=C4)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
MEN1 O00255 3/20 0.37
RAB9A P51151 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
NPC1 O15118 3/20 0.34
ERN1 O75460 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25106661 1.00 GPR84 (0.39) GPR84MEN1RAB9AKMT2AMAPT
SCHEMBL7269772 0.88 GPR84 (0.42) GPR84MEN1KMT2AMAPTLMNA
SCHEMBL25106659 0.87 NPC1 (0.46) MEN1RAB9AKMT2AMAPTLMNA
SCHEMBL361912 0.81 LCK (0.45) GPR84RAB9AMAPTERN1ALDH1A1
SCHEMBL20565372 0.77 GPR84 (0.32) GPR84
SCHEMBL20566123 0.77 GPR84 (0.32) GPR84MEN1KMT2AMAPTLMNA
SCHEMBL20566134 0.77 GPR84 (0.32) GPR84MEN1KMT2AMAPTLMNA
SCHEMBL2134543 0.76 CYP11B1 (0.41) MEN1RAB9AKMT2AMAPTNPC1
SCHEMBL7723531 0.74 CYP11B1 (0.41) MEN1RAB9AKMT2AMAPTNPC1
SCHEMBL20565377 0.74 MAPT (0.39) MEN1KMT2AMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023034402-A1 PHOTOINITIATORS, PHOTOHARDENABLE COMPOSITIONS, AND METHODS FOR FORMING AN OBJECT IN A VOLUME QUADRATIC 3D, INC. (US) 2023-03-09 WO disclosed