Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061587 | 0.92 | ALOX5 (0.43) | LCKALOX5KIF11GPR84TSHR | |
| SCHEMBL10026219 | 0.83 | TSHR (0.36) | ALOX5KIF11TSHRPTPN1KDM4E | |
| SCHEMBL7128812 | 0.82 | MAPT (0.40) | HTTKDM4EALDH1A1GAAPKM | |
| SCHEMBL5264237 | 0.81 | CYP1A2 (0.41) | ALOX5HTTKDM4EALDH1A1GAA | |
| SCHEMBL4253743 | 0.79 | APP (0.37) | PTPN1HTTKDM4EALDH1A1GAA | |
| SCHEMBL19107571 | 0.78 | RAB9A (0.45) | TSHRHTTKDM4EALDH1A1GAA | |
| SCHEMBL15157836 | 0.78 | HTT (0.41) | PTPN1HTTKDM4EALDH1A1GAA | |
| Acrylic Acid Methyl Ester SCHEMBL15158021 | 0.78 | HTT (0.41) | PTPN1HTTKDM4EALDH1A1GAA | |
| SCHEMBL5647064 | 0.77 | GAA (0.42) | TSHRALOX15KDM4EALDH1A1GAA | |
| SCHEMBL7126396 | 0.76 | CYP1A2 (0.36) | HTTKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| EP-1753838-B1 | POLYMERISABLE NAPHTHOPYRAN DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM SAID DERIVATIVES | POLYMEREXPERT S A (FR) | 2012-03-14 | — | — | EP | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| EP-1834195-B9 | PHOTOCHROMIC INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2010-07-21 | — | — | EP | disclosed |
| EP-1834195-B1 | PHOTOCHROMIC INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2010-03-17 | — | — | EP | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | CCND3, H1-3, H1-0 | LCK 4268/4885ALOX5 1758/4885KIF11 1395/4885 |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | C1S, H1-0, H1-3 | LCK 3808/4885ALOX5 1614/4885KIF11 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.