Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 6/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 6/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 5/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966137 | 1.00 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL30285076 | 0.87 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL28966151 | 0.87 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL30285229 | 0.86 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC2POLB | |
| SCHEMBL28966146 | 0.86 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC2POLB | |
| SCHEMBL18668657 | 0.79 | KDR (0.70) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL16456367 | 0.77 | POLB (0.73) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL24522646 | 0.76 | HDAC6 (0.74) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL18668729 | 0.76 | HDAC6 (0.62) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL18668668 | 0.76 | HDAC6 (0.73) | HDAC6HDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784986-A | HDAC6 inhibitor and preparation method and application thereof | 中国海洋大学 | 2023-03-14 | — | — | CN | claimed |
| CN-115784986-A | HDAC6 inhibitor and preparation method and application thereof | 中国海洋大学 | 2023-03-14 | — | — | CN | disclosed |