SCHEMBL30285402

SCHEMBL30285402

CC1(C)CC(=O)C=C(/C=C/c2cccc(Cl)c2)C1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 1/20 0.53
CHAT P28329 1/20 0.45
RELA Q04206 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAOB P27338 3/20 0.43
MAOA P21397 1/20 0.43
FBP1 P09467 1/20 0.42
AKR1C3 P42330 1/20 0.40
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
ADORA2A P29274 1/20 0.39
PIM1 P11309 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28884269 1.00 KMT2A (0.53) KMT2AMEN1ALDH1A1CHATRELA
SCHEMBL10474503 1.00 KMT2A (0.53) KMT2AMEN1ALDH1A1CHATRELA
SCHEMBL30285381 0.85 NFE2L2 (0.53) KMT2AMEN1ALDH1A1RELAMAOB
SCHEMBL28511276 0.85 NFE2L2 (0.53) KMT2AMEN1ALDH1A1RELAMAOB
SCHEMBL28360260 0.85 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1RELAMAOB
SCHEMBL30285208 0.85 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1RELAMAOB
SCHEMBL28360259 0.85 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1RELAMAOB
SCHEMBL28360476 0.85 NFE2L2 (0.53) KMT2AMEN1ALDH1A1RELAMAOB
SCHEMBL30285450 0.84 ALDH1A1 (0.51) KMT2AMEN1ALDH1A1MAOBMAOA
SCHEMBL28363906 0.83 KMT2A (0.57) KMT2AMEN1ALDH1A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110668950-B Chiral delta-nitroketene compound and asymmetric synthesis method and application thereof 浙江工业大学 2023-03-31 CN disclosed