Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26186454 | 1.00 | KMT2A (0.57) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL24173310 | 0.95 | RECQL (0.51) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL30285581 | 0.95 | RECQL (0.51) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL26186465 | 0.93 | SMN1; SMN2 (0.56) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL30285408 | 0.93 | SMN1; SMN2 (0.56) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL30285800 | 0.91 | SMN1; SMN2 (0.56) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL24173309 | 0.91 | SMN1; SMN2 (0.56) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL30285748 | 0.90 | SMN1; SMN2 (0.55) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL26186460 | 0.90 | SMN1; SMN2 (0.55) | KMT2ATSHRNPSR1SMN1; SMN2MAPT | |
| SCHEMBL30285823 | 0.87 | RECQL (0.49) | KMT2ATSHRNPSR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| US-20230257351-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-17 | — | — | US | disclosed |
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257351-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | P2RX2, P2RX5, P2RX3 | KMT2A 2416/4885TSHR 1571/4885NPSR1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.