Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005426 | 1.00 | TP53 (0.38) | TP53ALDH1A1KCNJ1KCNH2HTT | |
| SCHEMBL30285794 | 0.86 | VCAM1 (0.37) | TP53ALDH1A1MAPTPIK3CDPIK3CA | |
| SCHEMBL29005418 | 0.86 | VCAM1 (0.37) | TP53ALDH1A1MAPTPIK3CDPIK3CA | |
| SCHEMBL30285365 | 0.85 | VCAM1 (0.36) | TP53ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29005462 | 0.85 | VCAM1 (0.36) | TP53ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30285745 | 0.83 | TP53 (0.47) | TP53ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL29005766 | 0.83 | MEN1 (0.45) | TP53ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL29005482 | 0.83 | ALDH1A1 (0.46) | TP53ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL30285884 | 0.83 | ALDH1A1 (0.46) | TP53ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL30285811 | 0.83 | MEN1 (0.45) | TP53ALDH1A1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |