Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.45 |
| ▸ | ACLY | P53396 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | SGK1 | O00141 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355184 | 1.00 | CCR2 (0.45) | CCR2ACLYBRD4KITMCL1 | |
| SCHEMBL30286604 | 0.90 | CCR2 (0.46) | CCR2ACLYKITMCL1SGK1 | |
| SCHEMBL20355355 | 0.90 | CCR2 (0.46) | CCR2ACLYKITMCL1SGK1 | |
| SCHEMBL20339152 | 0.90 | CCR2 (0.45) | CCR2ACLYMCL1SGK1HPGD | |
| SCHEMBL20340299 | 0.89 | CCR2 (0.44) | CCR2ACLYKITSGK1NR4A2 | |
| SCHEMBL30286440 | 0.87 | ACLY (0.48) | CCR2ACLYKITMCL1SGK1 | |
| SCHEMBL20354678 | 0.87 | ACLY (0.48) | CCR2ACLYKITMCL1SGK1 | |
| SCHEMBL20340344 | 0.87 | CCR2 (0.52) | CCR2ACLYMCL1SGK1HPGD | |
| SCHEMBL20340297 | 0.86 | CCR2 (0.43) | CCR2ACLYMCL1SGK1HPGD | |
| SCHEMBL30286542 | 0.86 | CCR2 (0.43) | CCR2ACLYMCL1SGK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |