Cibacron Blue

Cibacron Blue

SCHEMBL30286286

Nc1c(S(=O)(=O)O)cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccccc4S(=O)(=O)O)n3)c(S(=O)(=O)O)c2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 1.00
CHAT P28329 4/20 0.85
USP2 O75604 2/20 0.85
APEX1 P27695 2/20 0.85
ENPP3 O14638 1/20 0.82
ENPP1 P22413 1/20 0.82
P2RX2 Q9UBL9 2/20 0.77
P2RX7 Q99572 1/20 0.77
P2RY1 P47900 2/20 0.77
FUT8 Q9BYC5 2/20 0.77
P2RY12 Q9H244 5/20 0.71
P2RY4 P51582 4/20 0.68
MEN1 O00255 1/20 0.68
LMNA P02545 1/20 0.68
TP53 P04637 1/20 0.68
POLB P06746 1/20 0.68
CYP3A4 P08684 1/20 0.68
GAA P10253 1/20 0.68
CYP2D6 P10635 1/20 0.68
MAPT P10636 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cibacron Blue SCHEMBL4350042 1.00 HPGDS (1.00) HPGDSCHATUSP2APEX1ENPP3
Cibacron Blue SCHEMBL29373073 1.00 HPGDS (1.00) HPGDSCHATUSP2APEX1ENPP3
Cibacron Blue SCHEMBL29558558 1.00 HPGDS (1.00) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL17000442 0.97 HPGDS (0.95) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL13213990 0.95 HPGDS (0.91) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL13046386 0.94 CHAT (0.90) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL12662265 0.93 HPGDS (0.86) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL11885371 0.93 HPGDS (0.86) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL19524846 0.93 HPGDS (0.86) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL13856914 0.92 CHAT (1.00) HPGDSCHATUSP2APEX1ENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153617-A1 PREPARATION AND PURIFICATION OF HYPERSIALYLATED IGG Momenta Pharmaceuticals, Inc. (US) 2023-03-29 EP disclosed