Cibacron Blue

Cibacron Blue

SCHEMBL29558558

Nc1c(S(=O)(=O)O)cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccccc4S(=O)(=O)O)n3)c(S(=O)(=O)O)c2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 1.00
CHAT P28329 4/20 0.85
USP2 O75604 2/20 0.85
APEX1 P27695 2/20 0.85
ENPP3 O14638 1/20 0.82
ENPP1 P22413 1/20 0.82
P2RX2 Q9UBL9 2/20 0.77
P2RX7 Q99572 1/20 0.77
P2RY1 P47900 2/20 0.77
FUT8 Q9BYC5 2/20 0.77
P2RY12 Q9H244 5/20 0.71
P2RY4 P51582 4/20 0.68
MEN1 O00255 1/20 0.68
LMNA P02545 1/20 0.68
TP53 P04637 1/20 0.68
POLB P06746 1/20 0.68
CYP3A4 P08684 1/20 0.68
GAA P10253 1/20 0.68
CYP2D6 P10635 1/20 0.68
MAPT P10636 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cibacron Blue SCHEMBL30286286 1.00 HPGDS (1.00) HPGDSCHATUSP2APEX1ENPP3
Cibacron Blue SCHEMBL4350042 1.00 HPGDS (1.00) HPGDSCHATUSP2APEX1ENPP3
Cibacron Blue SCHEMBL29373073 1.00 HPGDS (1.00) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL17000442 0.97 HPGDS (0.95) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL13213990 0.95 HPGDS (0.91) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL13046386 0.94 CHAT (0.90) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL12662265 0.93 HPGDS (0.86) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL11885371 0.93 HPGDS (0.86) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL19524846 0.93 HPGDS (0.86) HPGDSCHATUSP2APEX1ENPP3
SCHEMBL13856914 0.92 CHAT (1.00) HPGDSCHATUSP2APEX1ENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618855-B2 Serum protein biomarker panel for idiopathic pulmonary fibrosis CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2026-05-05 US disclosed
EP-4713349-A1 METHOD FOR ISOLATING FETUIN-A PreviPharma GmbH (DE) 2026-03-25 EP disclosed
EP-4683579-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC Yeung, Jeffrey E. (US) 2026-01-28 EP disclosed
WO-2025245356-A1 NITRIC OXIDE RELEASING ARTICLES WITH ENHANCED ALBUMIN AFFINITY AND METHODS FOR MAKING AND USING THE SAME UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2025-11-27 WO disclosed
US-20250332292-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH COVALENTLY ATTACHED DYE FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-10-30 US disclosed
EP-4639175-A1 METHOD TO DETECT AND TREAT PERIPHERAL NEUROPATHY Ohio State Innovation Foundation (US) 2025-10-29 EP disclosed
US-12422433-B2 Blood biomarker that predicts persistent cognitive dysfunction after concussion THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-09-23 US disclosed
WO-2024235911-A1 METHOD FOR ISOLATING FETUIN-A PREVIPHARMA CONSULTING GMBH (DE) 2024-11-21 WO disclosed
EP-4427045-A1 METHOD FOR THE DIAGNOSIS OF MELANOMA IMG Pharma Biotech, S.L. (ES) 2024-09-11 EP disclosed
US-12085565-B2 SNTF is a blood biomarker for the diagnosis and prognosis of sports-related concussion THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-09-10 US disclosed
US-11899027-B2 Diagnostic methods based on lipid profiles RUBIO METABOLOMICS, S.L.U. (ES) 2024-02-13 US disclosed
US-20230393133-A1 BLOOD BIOMARKER THAT PREDICTS PERSISTENT COGNITIVE DYSFUNCTION AFTER CONCUSSION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-12-07 US disclosed
US-11779643-B2 Methods and compositions for the treatment of an inflammatory bowel disease CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2023-10-10 US disclosed
US-11761959-B2 Blood biomarker that predicts persistent cognitive dysfunction after concussion THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-09-19 US disclosed
US-11725026-B2 Compositions and methods for inhibiting lactate dehydrogenase a activity THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
WO-2023078892-A1 METHOD FOR THE DIAGNOSIS OF MELANOMA IMG PHARMA BIOTECH, S.L. (ES) 2023-05-11 WO disclosed
EP-3418430-B1 BLOOD BIOMARKERS THAT PREDICT PERSISTENT COGNITIVE DYSFUNCTION AFTER CONCUSSION UNIV PENNSYLVANIA (US) 2023-03-29 EP disclosed
US-20220411399-A1 CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS SYCHRONICITY PHARMA INC (US) 2022-12-29 US disclosed
US-20220113321-A1 NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2022-04-14 US disclosed
CN-110003172-B Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators 同步制药公司 2022-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332292-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH COVALENTLY ATTACHED DYE FOR MEDICAL APPLICATIONS CD44, CRYAA, ILK HPGDS 120/4885CHAT 1055/4885USP2 381/4885
US-20220411399-A1 CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS CRY1, CRY2, HCCS HPGDS 1858/4885CHAT 485/4885USP2 1349/4885
US-12618855-B2 Serum protein biomarker panel for idiopathic pulmonary fibrosis SERPINA6, PITPNB, MYO3A HPGDS 3842/4885CHAT 3410/4885USP2 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.