Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30286308 | 0.92 | ACACB (0.42) | TIPARPACACBSLC6A9CHRM4CHRM2 | |
| SCHEMBL26125507 | 0.88 | TIPARP (0.43) | TIPARPACACBSLC6A9CHRM4CHRM2 | |
| SCHEMBL26125223 | 0.82 | HPGD (0.42) | TIPARPACACBSLC6A9CHRM4CHRM2 | |
| SCHEMBL26125453 | 0.81 | ACACB (0.42) | TIPARPACACBSLC6A9CHRM2HDAC3 | |
| SCHEMBL28982957 | 0.79 | EIF2AK4 (0.48) | ACACBSLC6A9CHRM4CHRM2KDM4E | |
| SCHEMBL27173051 | 0.79 | TIPARP (0.47) | TIPARPACACBSLC6A9CHRM4CHRM2 | |
| SCHEMBL26122829 | 0.77 | ACACB (0.43) | TIPARPACACBCHRM4CHRM2HDAC3 | |
| SCHEMBL28982961 | 0.76 | TIPARP (0.51) | TIPARPCHRM2PARP1AOC3 | |
| SCHEMBL26124703 | 0.75 | HPGD (0.42) | ACACBSLC6A9CHRM4KDM4E | |
| SCHEMBL28968501 | 0.73 | GPR119 (0.48) | ACACBSLC6A9CHRM4CHRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785074-B | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023185073-A1 | PARP7 INHIBITOR AND USE THEREOF | 诺沃斯达药业(上海)有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-115785074-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2023-03-14 | — | — | CN | disclosed |