Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 6/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355336 | 1.00 | EDNRA (0.52) | EDNRAPTPN5PTPN2PTPN1HTR6 | |
| SCHEMBL20340306 | 0.83 | ACLY (0.44) | EDNRACASP6CTDSP1MAPT | |
| SCHEMBL30286450 | 0.83 | ACLY (0.44) | EDNRACASP6CTDSP1MAPT | |
| SCHEMBL30286476 | 0.79 | MAPT (0.55) | PTPN5DUSP3CASP6PTPN11CTDSP1 | |
| SCHEMBL20355042 | 0.79 | MAPT (0.55) | PTPN5DUSP3CASP6PTPN11CTDSP1 | |
| SCHEMBL30388425 | 0.79 | EDNRA (0.44) | EDNRAPTPN5PTPN2PTPN1HSPD1 | |
| SCHEMBL20354809 | 0.79 | EDNRA (0.44) | EDNRAPTPN5PTPN2PTPN1HSPD1 | |
| SCHEMBL20355348 | 0.79 | EDNRA (0.47) | EDNRAPTPN5PTPN2PTPN1HSPD1 | |
| SCHEMBL30286661 | 0.79 | EDNRA (0.47) | EDNRAPTPN5PTPN2PTPN1HSPD1 | |
| SCHEMBL20354798 | 0.77 | MEN1 (0.46) | EDNRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |