Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.45 |
| ▸ | IDH1 | O75874 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339188 | 0.84 | SLC22A12 (0.49) | MCL1HSP90AA1HSP90AB1PGRTSHR | |
| SCHEMBL30286600 | 0.84 | SLC22A12 (0.49) | MCL1HSP90AA1HSP90AB1PGRTSHR | |
| SCHEMBL20354676 | 0.81 | CCR2 (0.45) | MEN1KMT2APGR | |
| SCHEMBL29559998 | 0.81 | CCR2 (0.45) | MEN1KMT2APGR | |
| SCHEMBL30286523 | 0.77 | EDNRA (0.52) | EDNRAMAPT | |
| SCHEMBL20355336 | 0.77 | EDNRA (0.52) | EDNRAMAPT | |
| SCHEMBL30286466 | 0.76 | ALPL (0.43) | MEN1KMT2AEDNRAALDH1A1 | |
| SCHEMBL21545953 | 0.76 | ALPL (0.43) | MEN1KMT2AEDNRAALDH1A1 | |
| SCHEMBL20354813 | 0.75 | CSNK2A2 (0.46) | MEN1KMT2AMCL1TSHRALDH1A1 | |
| SCHEMBL30286837 | 0.75 | CSNK2A2 (0.46) | MEN1KMT2AMCL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |