Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355218 | 1.00 | EDNRA (0.45) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20339142 | 0.90 | POLB (0.50) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29560013 | 0.86 | SLC22A12 (0.47) | HTT | |
| SCHEMBL20354701 | 0.86 | SLC22A12 (0.47) | HTT | |
| SCHEMBL20355221 | 0.86 | KMT2A (0.48) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20355194 | 0.83 | MCL1 (0.42) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29560848 | 0.83 | TMPRSS4 (0.43) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20354700 | 0.83 | TMPRSS4 (0.43) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL30286695 | 0.83 | MCL1 (0.42) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL23620132 | 0.81 | EDNRA (0.45) | EDNRAPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |