Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355194 | 1.00 | MCL1 (0.42) | MCL1LMNAALDH1A1GLAL3MBTL1 | |
| SCHEMBL20339142 | 0.87 | POLB (0.50) | LMNAALDH1A1POLBHTTEDNRA | |
| SCHEMBL20354701 | 0.85 | SLC22A12 (0.47) | SCN9AHTT | |
| SCHEMBL29560013 | 0.85 | SLC22A12 (0.47) | SCN9AHTT | |
| SCHEMBL20355221 | 0.83 | KMT2A (0.48) | LMNAALDH1A1POLBHTTEDNRA | |
| SCHEMBL20355218 | 0.83 | EDNRA (0.45) | LMNAALDH1A1POLBHTTEDNRA | |
| SCHEMBL30286552 | 0.83 | EDNRA (0.45) | LMNAALDH1A1POLBHTTEDNRA | |
| SCHEMBL21545927 | 0.83 | POLB (0.46) | MCL1LMNAALDH1A1P2RX1POLB | |
| SCHEMBL30286565 | 0.83 | POLB (0.46) | MCL1LMNAALDH1A1P2RX1POLB | |
| SCHEMBL20339134 | 0.82 | LMNA (0.45) | LMNASCN9AP2RX1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |