Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 7/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545889 | 1.00 | TDO2 (0.39) | TDO2GPR84CCR2SLC6A4SGK1 | |
| SCHEMBL20339154 | 0.89 | MEN1 (0.37) | TDO2SLC6A4SGK1NR3C1NR4A2 | |
| SCHEMBL30286626 | 0.88 | SGK1 (0.41) | TDO2GPR84SLC6A4SGK1NR4A2 | |
| SCHEMBL21545876 | 0.88 | SGK1 (0.41) | TDO2GPR84SLC6A4SGK1NR4A2 | |
| SCHEMBL20354887 | 0.88 | MEN1 (0.45) | TDO2CCR2SLC6A4SGK1NR4A2 | |
| SCHEMBL20355181 | 0.87 | CCR2 (0.39) | TDO2CCR2SGK1NR4A2CCR4 | |
| SCHEMBL20354864 | 0.87 | TDO2 (0.39) | TDO2GPR84CCR2SGK1NR4A2 | |
| SCHEMBL28961597 | 0.86 | GPR17 (0.38) | TDO2GPR84SLC6A4SGK1NR3C1 | |
| SCHEMBL21545853 | 0.86 | KMT2A (0.40) | CCR2SGK1NR4A2MEN1KMT2A | |
| SCHEMBL30286594 | 0.86 | KMT2A (0.40) | CCR2SGK1NR4A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |