Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 11/20 | 0.39 |
| ▸ | SGK1 | O00141 | 3/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340319 | 1.00 | ACLY (0.39) | ACLYSGK1CCR2PTGES2CYP2C9 | |
| SCHEMBL30286518 | 0.93 | ACLY (0.42) | ACLYSGK1CCR2PTGES2CYP2C9 | |
| SCHEMBL20354889 | 0.93 | ACLY (0.42) | ACLYSGK1CCR2PTGES2CYP2C9 | |
| SCHEMBL30286608 | 0.88 | ACLY (0.38) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL30286575 | 0.88 | HSD11B1 (0.38) | ACLYSGK1CCR2PTGES2CYP2C9 | |
| SCHEMBL20354859 | 0.88 | ACLY (0.38) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL20355214 | 0.88 | HSD11B1 (0.38) | ACLYSGK1CCR2PTGES2CYP2C9 | |
| SCHEMBL20339066 | 0.86 | SLC22A12 (0.38) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL21545937 | 0.86 | ACLY (0.36) | ACLYSGK1CCR2PTGES2CYP2C9 | |
| SCHEMBL30286674 | 0.86 | ACLY (0.36) | ACLYSGK1CCR2PTGES2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |