Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 7/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339149 | 1.00 | MEN1 (0.40) | MEN1PABPC1KMT2ASGK1ACLY | |
| SCHEMBL20354727 | 0.87 | CLK1 (0.38) | SGK1ACLYCLK1CLK2CLK3 | |
| SCHEMBL30286443 | 0.87 | CLK1 (0.38) | SGK1ACLYCLK1CLK2CLK3 | |
| SCHEMBL20340319 | 0.85 | ACLY (0.39) | SGK1ACLYPTGES2PIK3CDPIK3CA | |
| SCHEMBL30286645 | 0.85 | ACLY (0.39) | SGK1ACLYPTGES2PIK3CDPIK3CA | |
| SCHEMBL30286674 | 0.82 | ACLY (0.36) | SGK1ACLYPTGES2PIK3CDPIK3CA | |
| SCHEMBL20355337 | 0.82 | ACLY (0.36) | SGK1ACLY | |
| SCHEMBL30286550 | 0.82 | ACLY (0.36) | SGK1ACLY | |
| SCHEMBL21545937 | 0.82 | ACLY (0.36) | SGK1ACLYPTGES2PIK3CDPIK3CA | |
| SCHEMBL30286673 | 0.81 | MAP3K20 (0.36) | SGK1CLK1CLK2CLK3CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |