Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26651006 | 1.00 | PTGS2 (0.36) | PTGS2PTGS1HTR2AKCNH2HTR2C | |
| SCHEMBL30287363 | 0.90 | ERN1 (0.41) | PTGS2PTGS1HTR2AKCNH2HTR2C | |
| SCHEMBL28996379 | 0.90 | ERN1 (0.41) | PTGS2PTGS1HTR2AKCNH2HTR2C | |
| SCHEMBL25189031 | 0.86 | POLB (0.40) | PTGS2PTGS1KCNH2POLBKMT2A | |
| SCHEMBL31019968 | 0.86 | POLB (0.40) | PTGS2PTGS1KCNH2POLBKMT2A | |
| SCHEMBL28996389 | 0.84 | PTGS2 (0.40) | PTGS2PTGS1SCN9APOLBKIT | |
| SCHEMBL30287358 | 0.84 | PTGS2 (0.40) | PTGS2PTGS1SCN9APOLBKIT | |
| SCHEMBL30287367 | 0.83 | PTGS2 (0.38) | PTGS2PTGS1SCN9APOLBKIT | |
| SCHEMBL28996387 | 0.83 | PTGS2 (0.38) | PTGS2PTGS1SCN9APOLBKIT | |
| SCHEMBL30963578 | 0.83 | MEN1 (0.40) | PTGS2PTGS1HTR2AHTR2CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884968-B | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-115884968-A | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2023-03-31 | — | — | CN | disclosed |