Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28996379 | 1.00 | ERN1 (0.41) | ERN1MEN1KMT2APABPC1PTGS1 | |
| SCHEMBL26651006 | 0.90 | PTGS2 (0.36) | MEN1KMT2APTGS1PTGS2KCNH2 | |
| SCHEMBL30287361 | 0.90 | PTGS2 (0.36) | MEN1KMT2APTGS1PTGS2KCNH2 | |
| SCHEMBL30287307 | 0.88 | OXTR (0.38) | ERN1MEN1KMT2APABPC1PTGS1 | |
| SCHEMBL31019967 | 0.88 | ERN1 (0.40) | ERN1MEN1KMT2APABPC1PTGS1 | |
| SCHEMBL25275117 | 0.88 | OXTR (0.38) | ERN1MEN1KMT2APABPC1PTGS1 | |
| SCHEMBL25199320 | 0.88 | ERN1 (0.40) | ERN1MEN1KMT2APABPC1PTGS1 | |
| SCHEMBL25189031 | 0.85 | POLB (0.40) | ERN1KMT2APTGS1PTGS2KCNH2 | |
| SCHEMBL31019968 | 0.85 | POLB (0.40) | ERN1KMT2APTGS1PTGS2KCNH2 | |
| SCHEMBL28997127 | 0.84 | MEN1 (0.36) | MEN1KMT2APABPC1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451060-A | Pyrrole derivative or pharmaceutically acceptable salt thereof and composition for preventing, improving or treating gastrointestinal diseases comprising the same as active ingredient | 合娜制药株式会社 | 2024-08-06 | — | — | CN | disclosed |
| CN-115884968-B | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-115884968-A | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2023-03-31 | — | — | CN | disclosed |