Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092152 | 0.88 | PLA2G10 (0.49) | MEN1KMT2APLA2G10RXFP1L3MBTL1 | |
| SCHEMBL12011418 | 0.86 | MEN1 (0.42) | MEN1KMT2APLA2G10RXFP1L3MBTL1 | |
| SCHEMBL5600063 | 0.85 | KDM4E (0.44) | MEN1KMT2APLA2G10RXFP1L3MBTL1 | |
| SCHEMBL13557434 | 0.82 | KDM4E (0.55) | MEN1KMT2ARXFP1L3MBTL1KDM4E | |
| SCHEMBL20455602 | 0.80 | MEN1 (0.42) | MEN1KMT2ARXFP1L3MBTL1KDM4E | |
| SCHEMBL3760854 | 0.80 | KDM4E (0.39) | MEN1KMT2APLA2G10RXFP1KDM4E | |
| SCHEMBL12011416 | 0.78 | MEN1 (0.41) | MEN1KMT2ARXFP1L3MBTL1KDM4E | |
| SCHEMBL15273734 | 0.78 | MEN1 (0.43) | MEN1KMT2ARXFP1L3MBTL1KDM4E | |
| SCHEMBL24914933 | 0.76 | LMNA (0.51) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL2338097 | 0.76 | SMN1; SMN2 (0.46) | MEN1KMT2APLA2G10KDM4EGRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157828-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |