Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24009066 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HCRTR1HSD17B10CFTRKCNK3 | |
| SCHEMBL23294932 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HCRTR1HSD17B10MAPTL3MBTL1 | |
| SCHEMBL26696240 | 0.86 | MAPT (0.51) | ALDH1A1HSD17B10CFTRTDP1MAPT | |
| SCHEMBL24009070 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CFTRMAPTL3MBTL1 | |
| SCHEMBL10911414 | 0.83 | CYP3A4 (0.51) | ALDH1A1HCRTR1HSD17B10KCNK3KCNK9 | |
| SCHEMBL1320478 | 0.83 | L3MBTL1 (0.50) | ALDH1A1HCRTR1HSD17B10KCNK3KCNK9 | |
| SCHEMBL7534598 | 0.83 | CYP3A4 (0.50) | ALDH1A1HCRTR1KCNK3KCNK9MAPT | |
| SCHEMBL1004686 | 0.83 | HSD17B10 (0.56) | ALDH1A1HSD17B10CFTRKCNK3KCNK9 | |
| SCHEMBL1989129 | 0.83 | HCRTR1 (0.65) | ALDH1A1HCRTR1KCNK3KCNK9TDP1 | |
| SCHEMBL30553984 | 0.83 | HCRTR1 (0.65) | ALDH1A1HCRTR1KCNK3KCNK9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146344-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | Volastra Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |