Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 11/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384752 | 0.88 | SLC6A3 (0.46) | SLC6A3HPGDSEGFRERBB2SRC | |
| SCHEMBL24009103 | 0.83 | SLC6A3 (0.56) | SLC6A3HPGDSEGFRERBB2SRC | |
| SCHEMBL30288432 | 0.83 | SLC6A3 (0.56) | SLC6A3HPGDSEGFRERBB2SRC | |
| SCHEMBL24010646 | 0.78 | SLC6A3 (0.40) | SLC6A3SRCALDH1A1 | |
| SCHEMBL20562187 | 0.75 | IMPDH2 (0.49) | SLC6A3IMPDH2IMPDH1KDM4EUSP2 | |
| SCHEMBL6382093 | 0.74 | SLC6A3 (0.46) | SLC6A3HPGDSEGFRERBB2SRC | |
| SCHEMBL6381846 | 0.71 | SRC (0.57) | EGFRERBB2SRC | |
| SCHEMBL6379607 | 0.70 | SRC (0.68) | EGFRERBB2SRC | |
| SCHEMBL24715842 | 0.70 | SLC6A3 (0.39) | SLC6A3EGFRKDM4E | |
| SCHEMBL30666122 | 0.70 | MAP2K1 (0.36) | SLC6A3HPGDSEGFRERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146344-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | Volastra Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |